High Intensity Focused Ultrasound
for Prostate Cancer

Urologist serving Houston, Tomball, Magnolia, The Woodlands, Montgomery, Conroe, Willowbrook and CyFair

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Your Sonablate® HIFU Treatment

Who is a Candidate for HIFU with the Sonablate® 500?

sonablate hifu montgomerySonablate® HIFU may be effective for men who have early stage, localized prostate cancer that has not spread or metastasized outside the prostate. It is recommended that you discuss your individual medical records and history with a physician in order to confirm whether or not you are a candidate forSonablate® HIFU.

Sonablate® HIFU may also be an effective therapy for recurrent prostate cancer when patients may not have any other treatment options. Many patients, who have had primary therapy for prostate cancer, experience a rise in PSA years later and discover that the cancer is back. These patients may be candidates for the Sonablate® HIFU treatment as well.

The Sonablate® HIFU Procedure

Before HIFU Patients are given two enemas two hours prior to the procedure. It is very important that the patient does not move during Sonablate® HIFU thus patients are given an epidural (spinal) anesthesia and light intravenous sedation. During HIFU There is no pain during treatment. A small probe inserted into the rectum emits ultrasound waves directly to the prostatic tissue. During the procedure, the Sonablate® 500 delivers real-time images of the prostate and the surrounding area giving the physician immediate and detailed feedback. Treatment time varies, but generally lasts one to four hours, depending on the size of the prostate. After HIFU Immediately after Sonablate® HIFU patients typically spend one to two hours recovering at the treatment facility and then are discharged. The doctor will prescribe medications, but most patients do not experience any pain after the procedure. A catheter is inserted for two to four weeks to ensure the bladder empties properly. Patients should have their PSA checked three months after the procedure.

Effectiveness of the Sonablate® HIFU

HIFU has been studied extensively in Japan and Europe. Studies and presentations from outside the United States report that HIFU is a technique broadly comparable to standard therapies for the treatment for prostate cancer.2 A Japanese 3-year study of HIFU in patients who had a pre-HIFU PSA <10, had a biochemical disease free rate of 94%.3 Potential Side Effects and Complications All treatments for prostate cancer carry some risk for potential side effects and complications. Side effects include frequency, urgency, mild discomfort or discharge in urinary stream. Studies performed outside the US report that less common side effects (these may be more severe) may also include urinary stricture, retention, incontinence, impotence and rectal fistula. As with any medical procedure, all potential side effects and complications should be discussed with a physician before undergoing therapy. For a complete list of all possible risks associated with HIFU please refer to www.InternationalHIFU.com.

2 Illing, R., Chapman, A. The clinical applications of high intensity focused ultrasound in the prostate. Int. J. Hyperthermia, March 2007 23(2):183-191.

3 Toyaki U., Shiro B., Akira I., et al., Transrectal high-intensity focused ultrasound in the treatment of localized prostate cancer: A multicenter study.Acta Urol. Jpn. Vol. 51, No. 10, 2005.)

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